Sometimes you need to assign more then one email address
to one object (user or group) from various reasons and make this new
email address the default email address (this is email address that the
recipient side will see and reply).

In Exchange 2000 / 2003 servers all you have to do, is to create the new email address, mark it and click the
Set as primary option:

In Exchange 2007, you can not set the new email address as primary in the ordinarily way and the option for
Set as Reply (which is the same as Set as primary option – is grayed out):

In order to change the default email address, you must first have to unmark the
Automatically update e-mail addresses based on recipient policy (you will see that the
Set as primary option – is no longer grayed out):



Notice: If you
unmarked this option and you make changes in the email address policies
(under the Hub transport role) – those changes will NOT take effect on
this user:

Now, mark the new email address and click on the
Set as primary option:

Important: After you have changed the default email address – it will not be changed automatically in the AD:

Change the manually the primary email address in the AD:

This process of removing the Automatically update e-mail addresses based on recipient policy in order to change the default email address, is by design.